Thirupampuram is located 7 km west of Peralam. Tiruppaampuram is considered to be the 59th in the series of Tevara Stalams in the Chola kingdom located south of the river Kaveri.
The king of serpents Nagarajan, Karkotakan, Bhrama and Agasthyar are said to have worshipped Shiva here. The name Paampuram comes from the association with Nagarajan. Shiva here is also referred to as Seshapureeswarar, Sarpeswarar. Goddess of this temple is also known as Pramarambikai.
Legend: Aadisesha the mount of Vishnu worshipped Shiva here on the night of Shivaratri and that he commenced his worshipped at Kudandai Keezhkottam, and then proceeded through Tirunageswaram, Tiruppaampuram and Nagur. This event is celebrated on Mahasivaratri nights.
Offering worship at Kudandai Keezhkottam which is known as Nageswarar temple, Kumbakonam in the morning, at Tirunageswaram at noon and at Tiruppampuram in the evening on a given day is considered to be of special significance.
The place is sung in the Thevaram hymns of Thirugnanasambandar. There are shrines to Malaiyeeswarar, Bhairava, Surya, Mahavishnu, Bhrahma, Aadiseshan, Saneeswaran and others. If a snake enters in to home, it never bite any one in this place.